Tumors of the female reproductive system
PROGNOSTIC AND PREDICTIVE FACTORS IN TUMORS OF THE FEMALE REPRODUCTIVE SYSTEM, BREAST AND COLON
Principle investigator:
Prof. Snježana Tomić, MD, PhD
Members of the research team:
Prof. Katarina Vilović, MD, PhD
Ana Čarić, MD, MSc
Ana Poljičanin, MD
Joško Bezić, MD, MSc
Ivana Prović, MD
Dijana Gugić, MD
Dinka Šundov, MD
Branka Petrić, MD, MSc
Prof. Irena Drmić-Hoffman, PhD
Sendi Kuret, MSc
Željko Šundov, Phd
Prof. Ivana Kuzmić Prusac, MD, PhD
Prof. Eduard Vrdoljak, MD, PhD
Prof. Janoš Terzić, MD, PhD
Prof. Nikica Družijanić, MD, PhD
Assistant prof. Ivana Marinović Terzić, MD, PhD
Assistant prof. Deni Karelović, MD, PhD
Marko Mimica, MD, Phd
Boris Bačić, MD, MSc
Short description of the research:
This research group’s interests are mechanisms of carcinogenesis in tumors of female reproductive organs, breast and colon. We also study the clinical, pathohistological and molecular characteristics; both prognostic and predictive; for said types of tumors.
Ongoing projects:
1. Dualistic model of ovarian carcinogenesis – clinical, morphological and molecular study; sponsored by the Croatian Ministry of Science, Education and Sports – Principle investigator: Prof. Snježana Tomić, MD, PhD, project number: 216-0000000-0484
2. Role of apoptosis in cancerogenesis of the female genital tract; sponsored by the Croatian Ministry of Science, Education and Sports – Principle investigator: Prof. Katarina Vilović, MD, PhD, project number: 216-0000000-0479
3. Glycoprotein profile in normal and tumor cells. Sponsored by the Croatian Ministry of Science, Education and Sports – Principle investigator: Prof. Irena Drmić-Hoffman, PhD, project number: 141-0000000-0080
A list of our most important publications from this field (published in last three years):
1. Sundov Z, Kunac N, Puljak L, Capkun V, Druzijanic N, Capkun V. Cyclooxygenase-2 in Dukes B Colon Cancer: Hepatogastroeneterology 2010 (in press)
2. Mimica M, Tomic S, Kardum G, Drmic Hoffman I, Kaliterna V, Pejkovic L. Ki-67 Quantitative Evaluation as a Marker of Cervical Intraepithelial Neoplasia and Human papillomavirus Infection : Int J Gynecol Cancer 2010; 20: 116-119.
3. Bezic J, Tomic S, Kardum G. Minimal breast cancer in Split region of Croatia on the eve of the national mamogafphic program: Breast Journal 2009;: 5: 12
4. Sundov Z, Tomic S, Vilovic K, Kunac N, Kalebic M, Bezic J. Immunohistochemically detected high expression of matrix metalloproteinase-2 identifies poor prognosis in Duke’s B colon cancer. CMJ 2008; 49: 636-42
5. Projic P, Samija I, Bezic J, Tomic S, Andjelinovic S. Prognostic Significance of Ploidy and DNA Index in Patients with Epithelial Ovarian Carcinoma. Geburtsh Frauenheilk 2008;67: 475-9.
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