Laboratory for Cardiometabolic Research

Laboratory for Cardiometabolic Research

Laboratory for Cardiometabolic Research

  Laboratorj za kardiometabolička istraživanja

Head of Laboratory

Marko Kumrić, MD, PhD

Research
The focus of the Laboratory for Cardiometabolic Research is to investigate the ways in which various metabolic and immune system disorders such as obesity, diabetes, inflammatory bowel disease, obstructive sleep apnea, etc. are related to cardiovascular diseases. The laboratory specifically focuses on the role of various serum biomarkers in predicting cardiovascular outcomes in patients with heart failure, diabetes, hypertension, myocardial infarction and many others. In addition, an additional goal of the Laboratory is to investigate the impact of lifestyle changes on cardiovascular diseases and cardiovascular risk factors. In this regard, the Laboratory is extensively researching the impact of CBD on arterial pressure and other features of vascular health. Finally, with the arrival of the COVID-19 pandemic, we focused part of our research capacity on discovering the pathophysiological mechanisms underlying SARS-CoV-2 infection in patients with a severe form of COVID.
 
Projects:
Assoc. Prof. Joško Božić, MD, PhD
2018 - 2023 "Normative models of vascular biomarkers for improvement of cardiovascular risk stratification in primary and secondary prevention" financed by Croatian Science Foundation (HRZZ), associate
2014 - 2021 "Translational research on neuroplasticity of breathing and the effect of intermittent hypoxia in anesthesia and sleep" financed by Croatian Science Foundation (HRZZ), associate
2012 - 2013 "Croatian anatomical and physiological nomenclature - HRANAFINA" financed by Croatian Science Foundation (HRZZ), associate
2011 - 2013 "Scuba diving and the cardiovascular system" financed by Ministry of Science and Education (MZOŠ HR), associate
2011 - 2013 "Pathobiochemistry of glycosphingolipid antigens" financed by Ministry of Science and Education (MZOŠ HR), associate

Prof. Tina Tičinović Kurir, MD, PhD
2021 - 2024 "Biological, chronological and relative age in the function of the establishment of a national system of detection and development of sports talents", financed by Croatian Science Foundation (HRZZ), associate
2014 - 2021 "Translational research on neuroplasticity of breathing and the effect of intermittent hypoxia in anesthesia and sleep", financed by Croatian Science Foundation (HRZZ), associate
2007 - 2013 "Pathobiochemistry of glycosphingolipid antigens", financed by Ministry of Science and Education (MZOŠ HR), associate
2002 - 2006 "Glycosphingolipid expression in the regenerated rat liver" financed by Ministry of Science and Education (MZOŠ HR), associate
2001 - 2003 "Optimization of factors affecting liver regeneration",  financed by Ministry of Science and Education (MZOŠ HR), associate
 
Group members:
Assoc. Prof. Joško Božić, MD, PhD; principal investigator
Marko Kumrić, MD, PhD; Head of Lab
Prof. Tina Tičinović Kurir, MD, PhD; investigator
Assist. Prof. Marino Vilović, MD, PhD; investigator
Assist. Prof. Anteo Bradarić Šlujo, MD, PhD; investigator
Josip Vrdoljak, MD, PhD; investigator
Dinko Martinović, MD, PhD; external associate
Josip Anđelo Borovac, MD, PhD; external associate

Future directions 
The plans for Laboratory is to continue researching the pathophysiology of cardiovascular diseases and their connection with various metabolic disorders. First of all, the focus will be on further exploration of the impact of diabetes on heart function (diabetic cardiomyopathy) and on further research into the latent consequences of inflammatory bowel disease on the cardiovascular system.

Selected publications

Područja istraživanja: pathophysiology; cardiovascular system; cardiology; hypertension; diabetes mellitus; inflammatory bowel disease; obstructive sleep apnea; biomarkers 

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