Laboratory for biochemistry

Laboratory for biochemistry

We investigate glycophenotype changes as the causes and/or consequences of certain physiological and pathophysiological conditions as well as their responses.

Laboratory for biochemistry

 Laboratorij za biokemiju
Head of research group 
  
 Prof Vedrana Čikeš Čulić 
 
Research
Glycoantigens are the secondary gene products, that means their expression depends upon expression of specific glycosyltransferases and glycosidase which catalyse their synthesis and degradation, respectively. We investigate glycophenotype changes as the causes and/or consequences of certain physiological and pathophysiological conditions as well as their responses to drug therapies.

Active projects
RNazaH2A kao nova meta u dijagnostici i liječenju tumora mokraćnog mjehura
Lead researcher: Assist. Prof Vedrana Čikeš Čulić
Funded by Croatian Agency for SMEs, Innovations and Investments (HAMAG-BICRO)
Duration: jun 2016 - jun 2017
A. Markotić - Optimiranje čimbenika koji utječu na regeneraciju jetre 
 
Group members
Prof Vedrana Čikeš Čulić, PhD, lead researcher [CV]
Prof  Anita Markotić, PhD [CV]
Nikolina Režić Mužinić, PhD  [CV
Teaching Assist Angela Mastelić,  PhD  [CV]
Sandra Marijan, PhD, professional associate   [CV]
Future directions
Extension of cooperation in the frame of project „ Biological effects of wine: the influence of vinification technology, dealcoholization and aging of wine“ (No. 8652, PI Mladen Boban) supported by the Croatian Science Foundation. Our current results support critical monocyte subpopulation roles in modulation of the inflammatory microenvironment favourable for cardiomyocyte replenishment after myocardial infarction.
 

Selected publications and doctoral theses 

  
Interests and topics: glycoantigens; glycosphingolipids; gangliosides; high performance thin layer chromatography, HPTLC; HPTLC binding assay using choleragenoid; flow cytometry; cancer stem cells; myocardial infarction.  
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