Dental Biomaterials and Oral Care Products
Focuses on possible biological side effects of diverse kinds of biomaterials, as well oral care products.
Dental Biomaterials and Oral Care Products
Antonija Tadin, DMD, MSc, Ph.D., Assistant professor (📧)
(about)
Research
The Dental Biomaterials and Oral Care Products is research group that primarily focuses on possible biological side effects of diverse kinds of biomaterials, as well oral care products. So far, we have been investigating the toxicity of dental composites, adhesive systems, and glass-ionomer cements ex vivo on human pulp fibroblast, gingival fibroblasts, and lymphocytes (micronucleus and comet assay). However, all ex vivo studies are conducted under strictly controlled conditions, and those results should be taken with caution. Therefore, we recently focused our research interest on in vivo investigations.
Current research lines include:
(about)
Research
The Dental Biomaterials and Oral Care Products is research group that primarily focuses on possible biological side effects of diverse kinds of biomaterials, as well oral care products. So far, we have been investigating the toxicity of dental composites, adhesive systems, and glass-ionomer cements ex vivo on human pulp fibroblast, gingival fibroblasts, and lymphocytes (micronucleus and comet assay). However, all ex vivo studies are conducted under strictly controlled conditions, and those results should be taken with caution. Therefore, we recently focused our research interest on in vivo investigations.
Current research lines include:
- Biocompatibility of dental biomaterials (dental composites, glass-ionomer cement, dental implants, dental adhesives)
- Biocompatibility of oral care products (toothpaste)
- Clinical efficacy and safety of tooth whiting products
Publications:
- Gavić L, Goršeta K, Glavina D, Željezić D, Galić N, Tadin A. In vivo assessment of genotoxicity in buccal cells of children undergoing tooth restoration. Cent Eur J Public Health. 2019;27(4):312-319.
- Tadin A, Gavic L Govic T, Galic N, Zorica Vladislavic N, Zeljezic D. In vivo evaluation of fluoride and sodium lauryl sulphate in toothpaste on buccal epithelial cells toxicity. Acta Odontol Scand. 2019;77(5):386-393.
- Tadin A, Gavic L, Zeravica A, Ugrin K, Galic N, Zeljezic D. Assessment of cytotoxic and genotoxic effects of conventional and whitening kinds of toothpaste on oral mucosa cells. Acta Odontol Scand. 2018;76(1):64-70.
- Tadin A, Galic N, Marovic D, Gavic L, Klaric E, Pejda S, Ugrin K, Zeljzic D. Cytogenetic damage in exfoliated oral, buccal cells by dental composites. Am J Dent. 2016;29(4):219-222.
- Tadin A, Galic N, Mladinic M, Marovic D, Kovacic I, Zeljezic D. Composite-induced toxicity in human gingival and pulpal fibroblast cells. Acta Odontol Scand. 2014;72(4):304-11.
- Marovic D, Tadin A, Mladinic M, Juric-Kacunic D, Galic N. In vitro detection of DNA damage in human leukocytes induced by combined effect of composite resins and adhesive systems. Am J Dent. 2014;27(1):35-41.
- Tadin A, Galic N, Mladinic M, Marovic D, Kovacic I, Zeljezic D. Genotoxicity in gingival cells of patients undergoing tooth restoration with two different dental composite materials. Clin Oral Investig. 2014;18(1):87-96.
- Tadin A, Marovic D, Galic N, Milevoj A, Medvedec Mikic I, Zeljezic D. Genotoxic biomonitoring of flowable and non-flowable composite resins in peripheral blood leukocytes. Acta Odontol Scand. 2013;71(3-4):923-9.